Idk how unusual this is, but I'm playing a dex-based yuan ti rune knight currently. Shield and rapier, primarily melee. The original concept was to be a tanky character that has good general defenses and skills; a kind of all-rounder commando type. His personality and backstory has changed but the mechanics are the same and are pretty solid.

I had a barb/warlock too. Armor of Ag + rage is solid, and she also had the classic darkness/devil's sight combo. She kinda worked, but didn't scale all that well...once she got into t2, she needed to use rage just to survive so her other features became less useful/prominent.