The Shackles [PF2e Remaster]

[MechaKamuy]

Would you be ok with a PF2e newbie? I've played the beginner adventure, but not more. Looking to see how the game is with someone more experienced at the head.

Newbies are ok of course and the remaster edition is a good time to jump in.
I would recommend so you don't get too confused for now to stick to the following, since those options have been remastered: (other options technically have a remastered edit/option on Paizo website but it might get confusing for a beginner reading the errata for the remaster)

for Ancestries: Dwarf, Elf, Gnome, Goblin, Halfling, Human, Leshy, Orc and Versatile heritages (Changeling, Nephilim and Mixed Ancestry like Aivaurin or Dromaars or even a custom one all combos valid)
for classes: Bard, Cleric, Druid, Fighter, Ranger, Rogue, Witch and Wizard, (Kineticist is compatible with the Remaster edition but one player is already applying for it)

Don't worry about the Free archetype for now, as it will be relevant next level. Player Core 2 will cover more classes but it won't be out until this summer.

The isles of the Shackles are essentially pirates zone, there are many different cultures there.

The Firebrands
Not all factions have central bases of operation or organized hierarchies of command. The loosely affiliated freedom fighters, swashbuckling heroes, and
entertainers known as the Firebrands are one such group. They are united by a desire to fight oppression, oppose tyrannical regimes, rescue the wrongfully accused, and engage in jolly cooperation with like-minded heroes—all while building their own individual reputations and wealth. This group of defenders has proven surprisingly difficult for oppressive governments and cruel religions to defeat.

Regional Language:
For regional language that you have access to, Mwangi beside common (Taldane) is the most spoken language if you are a local of the Shackles.

About Alignments:
The remaster edition has removed alignments just something to keep in mind.