The Runners from the Hollows (SR5e)

[Llyarden]

The Hollows are not a part of SR lore, they're something I've made up as a substitute for a village that's important to the start of the game's plot in the PF adventure path.

From a cursory glance through the Shadowrun wikis, it seems like the mafia in the Sixth World is predominantly human and also generally discriminates against non-humans, but as I said I'm not going to super strictly enforce canon, so if you want to create a predominantly orkish family, feel free. As for whether they would care about the Hollows...from a general strategic perspective probably not, but if it's an area ostensibly under their protection they would act just for the sake of pride etc.