Motion blur is one of the two effects I immediately turn off when starting a new game (along with Chromatic Abberation). Irredeemably bad effects.

DoF I'm fine with because it makes it easier to tune out unimportant details without completely getting rid of ambiance.

I will say the after-images thing works for some games, I've been really liking it in Alan Wake 2, but that game is SUPPOSED to feel like you're in a dream (well, nightmare, specifically).