A43: No. A 20 on an attack roll is an automatic critical hit, no other modifiers are applied after that.
"If the d20 roll for an attack is a 20, the attack hits regardless of any modifiers or the target's AC."
There are mechanics that can disallow a crit (adamantine armor, etc.).
WARNING! Per the RAW a "crit" is only on an Attack Roll. It does not apply to a Skill Check nor a Saving Throw. For those you still apply modifiers and need to meet or exceed the DC set by the DM.